Scratches to Sketches
Monday, 24 November 2014
New Medical Studies on Cancer Causing Cellular Radiation Published
Hold that mobile phone away from your body ....
Received as email today:
Hello everyone,
It has been some months since we've held a formal meeting of the Lakeshore Coalition. A few of us have been kept busy with research and advocacy. I thought that you may appreciate receiving summaries of some of the most recent publications from the medical field and some informative videos which may help to explain what's happening when our bodies are exposed to the radiation from cell phones and other forms of wireless microwave radiation.
A wonderful video presentation was brought to my attention, conducted by Dr. Erica Mallery-Blythe which explains the effects of Wi-fi on children in schools. It is quite technical and very informative - hence, I thought you would appreciate watching it. https://www.youtube.com/watch?v=sNFdZVeXw7M&feature=youtu.be
There were a large number of physicians and scientists who have presented to the EESC open hearing on electrohypersensitivity in Brussels on the 4. november 2014 (European Economic and Social Committee). The presenters included in this recording include: Dr. Isaac Jamieson, UK and Dr. Olle Johansson, Karolinska Institute - Sweden. You can listen to their specific presentations if you scroll down the page a bit.
https://soundcloud.com/mastvictims/sets/eesc-hearing-on-electrohypersensitivity
You may also be interested to know that there is another medical organization closer to home which is working with Electro-hypersensitive patients in Ontario called the Myalgic Encephalomyelitis Association of Ontario (MEAO):
http://lindasepp.wordpress.com/2014/09/26/support-the-ontario-centre-of-excellence-in-environmental-health-oceeh/
Additionally, in September, the Women's College Hospital hosted an informational workshop for Physicians on the topic of Environmental Sensitivities. The presentations of guest speakers Dr. Devra Davis, Dr. Riina Bray, Dr. Anthony Miller and others are available for viewing at: http://www.c4st.org/MDSymposium.
You may also be interested to know that there is another medical organization closer to home which is working with Electro-hypersensitive patients in Ontario called the Myalgic Encephalomyelitis Association of Ontario (MEAO):
http://lindasepp.wordpress.com/2014/09/26/support-the-ontario-centre-of-excellence-in-environmental-health-oceeh/
Additionally, in September, the Women's College Hospital hosted an informational workshop for Physicians on the topic of Environmental Sensitivities. The presentations of guest speakers Dr. Devra Davis, Dr. Riina Bray, Dr. Anthony Miller and others are available for viewing at: http://www.c4st.org/MDSymposium.
This has been a busy month in the medical science area of Radio-Frequency Electromagnetic Field research. Two new studies have been published which clearly illustrate the link between cell phone use and brain tumours. (Of course this can soon be added to the effects of wind turbines as well because they transmit radar and are wireless-remotely controlled.) These have been forwarded to our own Lambton County Medical Officer of Health, Dr. Ranade.
First:
First:
Connection between Cell Phone use, p53 Gene Expression in Different Zones of Glioblastoma Multiforme and Survival Prognoses
2014 Aug 8
Abstract
The aim of this paper is to investigate p53 gene expression in the central and peripheral zones of glioblastoma multiforme (GBM) using a real-time reverse transcription polymerase chain reaction (RT-PCR) technique in patients who use cell phones ≥3 hours a day and determine its relationship to clinicopathological findings and overall survival.
Sixty-three patients (38 males and 25 females), diagnosed with GBM underwent tumor resection between 2008 and 2011. Patient ages ranged from 25 to 88 years, with a mean age of 55. The levels of expression of p53 in the central and peripheral zone of the GBM were quantified by RT-PCR. Data on p53 gene expression from the central and peripheral zone, the related malignancy and the clinicopatholagical findings (age, gender, tumor location and size), as well as overall survival, were analyzed.
Forty-one out of 63 patients (65%) with the highest level of cell phone use (≥3 hours/day) had higher mutant type p53 expression in the peripheral zone of the glioblastoma; the difference was statistically significant (P=0.034).
Results from the present study on the use of mobile phones for ≥3 hours a day show a consistent pattern of increased risk for the mutant type of p53 gene expression in the peripheral zone of the glioblastoma, and that this increase was significantly correlated with shorter overall survival time. The risk was not higher for ipsilateral exposure. We found that the mutant type of p53 gene expression in the peripheral zone of the glioblastoma was increased in 65% of patients using cell phones ≥3 hours a day.
94% of the tumors expressed a p53 mutation with a loss of normal protein function. Moreover, 65% of patients who used their cell phones more than 3 hours per day showed a significantly higher mutant p53 expression in the peripheral zone of the tumor compared to the central zone, which was in turn significantly correlated with a shorter overall survival time.
The authors concluded that these results show a relationship between cell phone use, the occurrence of p53 in the peripheral zone of GBM and overall survival time, and that further studies should be conducted.
http://1.usa.gov/13JdS89
Also see:
Carlberg M, Hardell L. Decreased Survival of Glioma Patients with Astrocytoma Grade IV (Glioblastoma Multiforme) Associated with Long-Term Use of Mobile and Cordless Phones. International Journal of Environmental Research and Public Health. 2014; 11(10):10790-10805.
Abstract
On 31 May 2011 the WHO International Agency for Research on Cancer (IARC) categorised radiofrequency electromagnetic fields (RF-EMFs) from mobile phones, and from other devices that emit similar non-ionising electromagnetic fields, as a Group 2B, i.e., a "possible", human carcinogen. A causal association would be strengthened if it could be shown that the use of wireless phones has an impact on the survival of glioma patients.
We analysed survival of 1678 glioma patients in our 1997–2003 and 2007–2009 case-control studies. Use of wireless phones in the >20 years latency group (time since first use) yielded an increased hazard ratio (HR) = 1.7, 95% confidence interval (CI) = 1.2–2.3 for glioma. For astrocytoma grade IV (glioblastoma multiforme; n = 926) mobile phone use yielded HR = 2.0, 95% CI = 1.4–2.9 and cordless phone use HR = 3.4, 95% CI = 1.04–11 in the same latency category. The hazard ratio for astrocytoma grade IV increased statistically significant per year of latency for wireless phones, HR = 1.020, 95% CI = 1.007–1.033, but not per 100 h cumulative use, HR = 1.002, 95% CI = 0.999–1.005. HR was not statistically significant increased for other types of glioma.
Due to the relationship with survival the classification of IARC is strengthened and RF-EMF should be regarded as human carcinogen requiring urgent revision of current exposure guidelines.
Open Access: http://bit.ly/1sW8KqG
Abstract
The aim of this paper is to investigate p53 gene expression in the central and peripheral zones of glioblastoma multiforme (GBM) using a real-time reverse transcription polymerase chain reaction (RT-PCR) technique in patients who use cell phones ≥3 hours a day and determine its relationship to clinicopathological findings and overall survival.
Sixty-three patients (38 males and 25 females), diagnosed with GBM underwent tumor resection between 2008 and 2011. Patient ages ranged from 25 to 88 years, with a mean age of 55. The levels of expression of p53 in the central and peripheral zone of the GBM were quantified by RT-PCR. Data on p53 gene expression from the central and peripheral zone, the related malignancy and the clinicopatholagical findings (age, gender, tumor location and size), as well as overall survival, were analyzed.
Forty-one out of 63 patients (65%) with the highest level of cell phone use (≥3 hours/day) had higher mutant type p53 expression in the peripheral zone of the glioblastoma; the difference was statistically significant (P=0.034).
Results from the present study on the use of mobile phones for ≥3 hours a day show a consistent pattern of increased risk for the mutant type of p53 gene expression in the peripheral zone of the glioblastoma, and that this increase was significantly correlated with shorter overall survival time. The risk was not higher for ipsilateral exposure. We found that the mutant type of p53 gene expression in the peripheral zone of the glioblastoma was increased in 65% of patients using cell phones ≥3 hours a day.
94% of the tumors expressed a p53 mutation with a loss of normal protein function. Moreover, 65% of patients who used their cell phones more than 3 hours per day showed a significantly higher mutant p53 expression in the peripheral zone of the tumor compared to the central zone, which was in turn significantly correlated with a shorter overall survival time.
The authors concluded that these results show a relationship between cell phone use, the occurrence of p53 in the peripheral zone of GBM and overall survival time, and that further studies should be conducted.
http://1.usa.gov/13JdS89
Also see:
Carlberg M, Hardell L. Decreased Survival of Glioma Patients with Astrocytoma Grade IV (Glioblastoma Multiforme) Associated with Long-Term Use of Mobile and Cordless Phones. International Journal of Environmental Research and Public Health. 2014; 11(10):10790-10805.
Abstract
On 31 May 2011 the WHO International Agency for Research on Cancer (IARC) categorised radiofrequency electromagnetic fields (RF-EMFs) from mobile phones, and from other devices that emit similar non-ionising electromagnetic fields, as a Group 2B, i.e., a "possible", human carcinogen. A causal association would be strengthened if it could be shown that the use of wireless phones has an impact on the survival of glioma patients.
We analysed survival of 1678 glioma patients in our 1997–2003 and 2007–2009 case-control studies. Use of wireless phones in the >20 years latency group (time since first use) yielded an increased hazard ratio (HR) = 1.7, 95% confidence interval (CI) = 1.2–2.3 for glioma. For astrocytoma grade IV (glioblastoma multiforme; n = 926) mobile phone use yielded HR = 2.0, 95% CI = 1.4–2.9 and cordless phone use HR = 3.4, 95% CI = 1.04–11 in the same latency category. The hazard ratio for astrocytoma grade IV increased statistically significant per year of latency for wireless phones, HR = 1.020, 95% CI = 1.007–1.033, but not per 100 h cumulative use, HR = 1.002, 95% CI = 0.999–1.005. HR was not statistically significant increased for other types of glioma.
Due to the relationship with survival the classification of IARC is strengthened and RF-EMF should be regarded as human carcinogen requiring urgent revision of current exposure guidelines.
Open Access: http://bit.ly/1sW8KqG
Second:
Low intensity radiofrequency radiation: a new oxidant for living cells
Igor Yakymenko, Evgeniy Sidorik, Diane Henshel, Sergiy Kyrylenko. Editorial. Low intensity radiofrequency radiation: a new oxidant for living cells. Oxid Antioxid Med Sci. 2014; 3(1): 1-3. doi: 10.5455/oams.240314.ed.002.
No abstract
Radiofrequency radiation (RFR), e.g. electromagnetic waves emitted by our cell phones and Wi-Fi, are referred to as non-ionizing. This means that in contrast to the ionizing radiation, which does induce ionization of water and biologically important macromolecules, RFR does not have a capacity for such effects. Unlike, for example X-rays, the energy of RFR is not enough to break electrons off the molecules. However, is RFR completely safe for public health? Traditionally, the industry and the public bodies said yes. Nevertheless, new research data change this perception.
http://www.scopemed.org/?mno=154583
Open Access Paper: http://www.scopemed.org/fulltextpdf.php?mno=154583
Excerpts
Unexpectedly, a strong non-thermal character of biological effects of RFR has been documented. As low as 0.1 μW/cm2 intensity of RFR and absorbed energy (specific absorption rate, SAR) of 0.3 μW/kg were demonstrated to be effective in inducing significant oxidative stress in living cells [27, 29]. This observation is particularly important as the modern international safety limits on RFR exposure are based solely on the thermal effects of the radiation and only restrict RFR intensity to 450-1000 μW/cm2 and SAR to 2 W/kg [30]. Moreover, studies where thermal intensities of RFR have been used could not reveal oxidative effects [31-33], which might point to the variety of molecular mechanisms of action of radiation induced by different radiation intensities.
It is indicative that many studies demonstrated the effectiveness of different antioxidants to reverse the oxidative stress caused by RFR exposure. Such effects have been reported for melatonin [34-37], vitamins E and C [24, 38], caffeic acid phenethyl ester [36], selenium and L-carnitine [39], and garlic extract [40].
It is still a question how low intensity RFR could activate superoxide-generating enzyme NADH oxidase or significantly increase the level of NO in a cell (e.g., possibly due to activation of NO synthase). But what is understood at the moment is that significantly increased levels of ROS in living cells caused by low intensity RFR exposure could lead to mutagenic effects through expressive oxidative damage of DNA [17, 27, 41]. It is also well documented nowadays that in biological systems, oxidants are not necessarily always the triggers for oxidative damage, and that oxidants such as H2O2 could actually serve as signaling messengers and drive several aspects of cellular signaling [42]. This leads to a hypothesis that overproduction of ROS/free radical species in living cells under low intensity RFR exposure can lead to disturbances in cell signaling cascades, which in turn may result in various pathologic consequences.
Whatever the particular first-step molecular mechanisms, it is clear that the substantial overproduction of ROS in living cells under low intensity RFR exposure could cause a broad spectrum of health disorders and diseases, including cancer in humans. Undoubtedly, this calls for the further intensive research in the area, as well as to a precautionary approach in routine usage of wireless devices.
No abstract
Radiofrequency radiation (RFR), e.g. electromagnetic waves emitted by our cell phones and Wi-Fi, are referred to as non-ionizing. This means that in contrast to the ionizing radiation, which does induce ionization of water and biologically important macromolecules, RFR does not have a capacity for such effects. Unlike, for example X-rays, the energy of RFR is not enough to break electrons off the molecules. However, is RFR completely safe for public health? Traditionally, the industry and the public bodies said yes. Nevertheless, new research data change this perception.
http://www.scopemed.org/?mno=154583
Open Access Paper: http://www.scopemed.org/fulltextpdf.php?mno=154583
Excerpts
Unexpectedly, a strong non-thermal character of biological effects of RFR has been documented. As low as 0.1 μW/cm2 intensity of RFR and absorbed energy (specific absorption rate, SAR) of 0.3 μW/kg were demonstrated to be effective in inducing significant oxidative stress in living cells [27, 29]. This observation is particularly important as the modern international safety limits on RFR exposure are based solely on the thermal effects of the radiation and only restrict RFR intensity to 450-1000 μW/cm2 and SAR to 2 W/kg [30]. Moreover, studies where thermal intensities of RFR have been used could not reveal oxidative effects [31-33], which might point to the variety of molecular mechanisms of action of radiation induced by different radiation intensities.
It is indicative that many studies demonstrated the effectiveness of different antioxidants to reverse the oxidative stress caused by RFR exposure. Such effects have been reported for melatonin [34-37], vitamins E and C [24, 38], caffeic acid phenethyl ester [36], selenium and L-carnitine [39], and garlic extract [40].
It is still a question how low intensity RFR could activate superoxide-generating enzyme NADH oxidase or significantly increase the level of NO in a cell (e.g., possibly due to activation of NO synthase). But what is understood at the moment is that significantly increased levels of ROS in living cells caused by low intensity RFR exposure could lead to mutagenic effects through expressive oxidative damage of DNA [17, 27, 41]. It is also well documented nowadays that in biological systems, oxidants are not necessarily always the triggers for oxidative damage, and that oxidants such as H2O2 could actually serve as signaling messengers and drive several aspects of cellular signaling [42]. This leads to a hypothesis that overproduction of ROS/free radical species in living cells under low intensity RFR exposure can lead to disturbances in cell signaling cascades, which in turn may result in various pathologic consequences.
Whatever the particular first-step molecular mechanisms, it is clear that the substantial overproduction of ROS in living cells under low intensity RFR exposure could cause a broad spectrum of health disorders and diseases, including cancer in humans. Undoubtedly, this calls for the further intensive research in the area, as well as to a precautionary approach in routine usage of wireless devices.
Third:
Could Myelin Damage From Radiofrequency Electromagnetic Field Exposure Help Explain the Functional Impairment Electrohypersensitivity? A Review of the Evidence
Journal of Toxicology and Environmental Health, Part B: Critical Reviews
Volume 17, Issue 5, 2014
Mary Redmayneab* & Olle Johansson
Published online: 09 Sep 2014
Abstract
Myelin provides the electrical insulation for the central and peripheral nervous system and develops rapidly in the first years of life, but continues into mid-life or later. Myelin integrity is vital to healthy nervous system development and functioning. This review outlines the development of myelin through life, and then considers the evidence for an association between myelin integrity and exposure to low-intensity radiofrequency electromagnetic fields (RF-EMFs) typical in the modern world. In RF-EMF peer-reviewed literature examining relevant impacts such as myelin sheath, multiple sclerosis, and other myelin-related diseases, cellular examination was included. There are surprisingly little data available in each area, but considered together a picture begins to emerge in RF-EMF-exposed cases: (1) significant morphological lesions in the myelin sheath of rats; (2) a greater risk of multiple sclerosis in a study subgroup; (3) effects in proteins related to myelin production; and (4) physical symptoms in individuals with functional impairment electrohypersensitivity, many of which are the same as if myelin were affected by RF-EMF exposure, giving rise to symptoms of demyelination. In the latter, there are exceptions; headache is common only in electrohypersensitivity, while ataxia is typical of demyelination but infrequently found in the former group. Overall, evidence from in vivo and in vitro and epidemiological studies suggests an association between RF-EMF exposure and either myelin deterioration or a direct impact on neuronal conduction, which may account for many electrohypersensitivity symptoms. The most vulnerable are likely to be those in utero through to at least mid-teen years, as well as ill and elderly individuals.
http://www.tandfonline.com/doi/abs/10.1080/10937404.2014.923356#.VHNZnNLF-bC
Fourth:
Sharp increase in patients treated for brain tumors with unclear diagnosis in Sweden
An increasing number of patients are treated for brain tumor "of unknown nature" in Sweden since 2008, but the increase is not reflected in the national cancer registry. – It is serious if the statistics on new cases of brain tumors is incorrect because the brain tumor statistics is widely being used as an argument that cell phones do not increase the risk of cancer and brain tumors, says Mona Nilsson, Chairman of Swedish Radiation Protection Foundation.
Swedish Radiation Protection Foundation has compiled statistics from the Swedish Health Board registry's database on the number of patients treated for brain tumors in Sweden as well as from the cancer registry and cause of death registry, during the last decade. The number of people receiving treatment fora brain tumor"of unknown nature" increased by almost 30% only between 2008 and 2012. At the same time, the number of patients with a confirmed brain tumor diagnosis remained at a relatively stable level.
Read the rest of the article at the link below:
Read more: http://www.stralskyddsstiftelsen.se/2014/10/increase-brain-tumors/
An increasing number of patients are treated for brain tumor "of unknown nature" in Sweden since 2008, but the increase is not reflected in the national cancer registry. – It is serious if the statistics on new cases of brain tumors is incorrect because the brain tumor statistics is widely being used as an argument that cell phones do not increase the risk of cancer and brain tumors, says Mona Nilsson, Chairman of Swedish Radiation Protection Foundation.
Swedish Radiation Protection Foundation has compiled statistics from the Swedish Health Board registry's database on the number of patients treated for brain tumors in Sweden as well as from the cancer registry and cause of death registry, during the last decade. The number of people receiving treatment fora brain tumor"of unknown nature" increased by almost 30% only between 2008 and 2012. At the same time, the number of patients with a confirmed brain tumor diagnosis remained at a relatively stable level.
Read the rest of the article at the link below:
Read more: http://www.stralskyddsstiftelsen.se/2014/10/increase-brain-tumors/
I hope you will find this information useful and will share it with others freely, to aid the understanding of Electro-hypersensitivity and the effects of wireless microwave radiation from cell phones, Wi-fi, 'smart' meters, wireless baby monitors, wireless devices and industrial wind turbines. If you have any questions, please don't hesitate to ask.
L at Lakeshore Coalition
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Sketches from scratches is a provocative blogspot that has grown out of the Wuh Lax experience. It is eclectic, which means that it might consider just about anything from the simple to the extremely difficult. A scratch can be something that is troubling me or a short line on paper. From a scratch comes a verbal sketch or image sketch of the issue or subject. Other sites have other stuff that should really be of interest to the broad reader. I try to develop themes, but variety often comes before depth.
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